HitPredict

Interactor 1: CENPX (Q3E829)
Inner kinetochore subunit MHF2 (CENP-X homolog) (Constitutive centromere-associated network protein MHF2) (MHF histone-fold complex subunit 2) (MPH1-associated histone-fold protein 2)
Gene: MHF2

Interactor 2: CENPS (Q3E835)
Inner kinetochore subunit MHF1 (CENP-S homolog) (Constitutive centromere-associated network protein MHF1) (MHF histone-fold complex subunit 1) (MPH1-associated histone-fold protein 1)
Gene: MHF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.90 0.855

The method score is based on:

Property Details
Experiments 22325783, 26966246, 22696213, 22561346
Identification Methods pull down, molecular sieving, x-ray crystallography, affinity chromatography technology
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CENP-S~CENP-X
Common GO terms GO:0000712 - resolution of meiotic recombination intermediates
GO:0003677 - DNA binding
GO:0006281 - DNA repair
GO:0006974 - DNA damage response
GO:0031297 - replication fork processing
and 2 others

more...
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024