HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (p62)
Gene: SQSTM1

Interactor 2: RNF26 (Q9BY78)
E3 ubiquitin-protein ligase RNF26 (EC 2.3.2.27) (RING finger protein 26)
Gene: RNF26

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	27368102, 37519262
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006511 - ubiquitin-dependent protein catabolic process GO:0007032 - endosome organization GO:0008270 - zinc ion binding GO:1905719 - protein localization to perinuclear region of cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 433
+	Hs
		1106826 SQSTM_HUMAN (1-440): 0: 760: 100.00		BIRC3_HUMAN (321-433): 8.72e-28: 117: 23.01
+	Hs
		1107394 SQSTM_HUMAN (1-440): 0: 760: 100.00		BIRC2_HUMAN (321-433): 3.82e-25: 109: 23.01
+	Hs
		1022707 SQSTM_HUMAN (1-440): 0: 760: 100.00		XIAP_HUMAN (335-433): 3.48e-21: 97.5: 20.20
+	Hs
		1106863 NBR1_HUMAN (80-184): 5.97e-10: 63.6: 24.78		BIRC3_HUMAN (321-433): 8.72e-28: 117: 23.01