HitPredict

Interactor 1: PCGF3 (Q3KNV8)
Polycomb group RING finger protein 3 (RING finger protein 3A)
Gene: PCGF3

Interactor 2: PHC3 (Q8NDX5)
Polyhomeotic-like protein 3 (Early development regulatory protein 3) (Homolog of polyhomeotic 3) (hPH3)
Gene: PHC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031519 - PcG protein complex GO:0035102 - PRC1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 242 Hs			1 983
+	Hs
		718028 BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76		PHC3_HUMAN (1-983): 3.72e-88: 305: 100.00
+	Hs
		718412 PCGF2_HUMAN (3-238): 5.76e-59: 191: 34.03		PHC3_HUMAN (1-983): 3.72e-88: 305: 100.00
+	Mm
		639476 BMI1_MOUSE (3-238): 5e-59: 191: 33.48		PHC3_MOUSE (30-983): 1.26e-78: 278: 93.61
+	Hs
		554277 BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76		MUC1_HUMAN (2-764): 1.79e-44: 177: 11.56
+	Hs
		1108531 PCGF3_HUMAN (1-242): 8.16e-66: 205: 100.00		SCMH1_HUMAN (552-982): 1.15e-38: 155: 17.83
+	Hs
		943064 PCGF3_HUMAN (1-242): 8.16e-66: 205: 100.00		PHC1_HUMAN (33-983): 9.51e-36: 148: 23.90
+	Hs
		718098 BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76		SCMH1_HUMAN (552-982): 1.15e-38: 155: 17.83
+	Hs
		718418 PCGF2_HUMAN (3-238): 5.76e-59: 191: 34.03		SCMH1_HUMAN (552-982): 1.15e-38: 155: 17.83
+	Hs
		717684 BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76		PHC1_HUMAN (33-983): 9.51e-36: 148: 23.90
+	Hs
		718390 PCGF2_HUMAN (3-238): 5.76e-59: 191: 34.03		PHC1_HUMAN (33-983): 9.51e-36: 148: 23.90
+	Mm
		639473 BMI1_MOUSE (3-238): 5e-59: 191: 33.48		PHC1_MOUSE (33-983): 3.74e-35: 147: 24.25
+	Hs
		718330 BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76		SCML2_HUMAN (553-982): 5.47e-34: 141: 17.40
+	Dr
		1186373 BMI1B_DANRE (3-238): 4.71e-61: 196: 31.36		PHC2_DANRE (172-983): 1.93e-30: 131: 23.58
+	Hs
		718311 BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76		SCML1_HUMAN (799-982): 6.24e-33: 132: 22.28
+	Dr
		1225025 BMI1A_DANRE (3-238): 5.06e-60: 193: 33.05		PHC2_DANRE (172-983): 1.93e-30: 131: 23.58
+	Hs
		1108515 PCGF3_HUMAN (1-242): 8.16e-66: 205: 100.00		PHC2_HUMAN (30-566): 3.66e-17: 88.9: 27.02
+	Hs
		1220909 R4GMX3_HUMAN (3-238): 7.96e-59: 194: 33.76		PHC2_HUMAN (30-566): 3.66e-17: 88.9: 27.02
+	Hs
		717999 BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76		PHC2_HUMAN (30-566): 3.66e-17: 88.9: 27.02
+	Hs
		718408 PCGF2_HUMAN (3-238): 5.76e-59: 191: 34.03		PHC2_HUMAN (30-566): 3.66e-17: 88.9: 27.02
+	Mm
		639480 BMI1_MOUSE (3-238): 5e-59: 191: 33.48		PHC2_MOUSE (30-635): 2.17e-13: 76.6: 25.74