HitPredict

Interactor 1: CEA21 (Q3KPI0)
Carcinoembryonic antigen-related cell adhesion molecule 21
Gene: CEACAM21

Interactor 2: CDON (Q4KMG0)
Cell adhesion molecule-related/down-regulated by oncogenes
Gene: CDON

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ig_3~fn3, Ig_3~I-set, Ig_3~Ig_3, V-set~fn3, I-set~V-set, Ig_3~V-set
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 1287
+	Hs
		1336275 ROBO2_HUMAN (3-235): 3.56e-35: 136: 17.08		ROBO1_HUMAN (15-1262): 3.59e-146: 485: 17.37
+	Mm
		1149039 CNTN4_MOUSE (17-265): 3.1e-30: 121: 19.38		CNTN4_MOUSE (5-1069): 7.69e-143: 462: 18.00
+	Hs
		1378225 ROBO1_HUMAN (126-282): 8.31e-22: 97.6: 15.39		ROBO1_HUMAN (15-1262): 3.59e-146: 485: 17.37
+	Hs
		1336269 ROBO2_HUMAN (3-235): 3.56e-35: 136: 17.08		ROBO2_HUMAN (5-1155): 8.1e-129: 432: 16.89
+	Rn
		222935 DCC_RAT (5-264): 2.59e-15: 78.3: 9.82		ROBO1_RAT (15-1262): 2.19e-143: 477: 17.14
+	Hs
		1018295 CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00		CNTN1_HUMAN (15-918): 1.72e-85: 303: 16.51
+	Dm
		219801 O44924_DROME (32-179): 7.85e-13: 70.6: 13.91		O44924_DROME (21-1276): 2.6e-117: 400: 16.80
+	Hs
		1108780 CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00		SDK2_HUMAN (40-959): 1.43e-33: 143: 13.68
+	Ce
		103933 SAX3_CAEEL (145-292): 1.19e-20: 94.1: 16.25		SAX3_CAEEL (221-1008): 3.91e-63: 238: 16.67
+	Hs
		234601 ROBO1_HUMAN (126-282): 8.31e-22: 97.6: 15.39		DSCAM_HUMAN (109-1273): 7.74e-41: 167: 11.67
+	Hs
		685250 CEAM8_HUMAN (5-253): 2.17e-20: 91.4: 15.56		SDK2_HUMAN (40-959): 1.43e-33: 143: 13.68
+	Dm
		53783 Q9W213_DROME (32-179): 7.43e-13: 70.6: 13.91		A1Z920_DROME (253-519): 7.47e-10: 65.9: 25.70