HitPredict

Interactor 1: CEA21 (Q3KPI0)
Carcinoembryonic antigen-related cell adhesion molecule 21
Gene: CEACAM21

Interactor 2: NR3L1 (Q68D85)
Natural cytotoxicity triggering receptor 3 ligand 1 (B7 homolog 6) (B7-H6)
Gene: NCR3LG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1-set~Ig_3, C1-set~V-set
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 454
+	Hs
		1108782 CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00		CD276_HUMAN (1-396): 1.95e-39: 150: 18.01
+	Hs
		1108799 CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00		NECT2_HUMAN (21-261): 2.04e-31: 128: 20.23
+	Hs
		545117 CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00		PVR_HUMAN (18-261): 5.52e-32: 128: 23.29
+	Hs
		382443 CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00		HLAA_HUMAN (113-296): 5.54e-30: 121: 20.86
+	Mm
		1257561 CD276_MOUSE (71-231): 2.24e-17: 82.4: 21.02		CD276_MOUSE (5-290): 8.97e-40: 147: 19.72
+	Hs
		382329 VGFR3_HUMAN (38-238): 2.33e-16: 81.3: 16.75		HLAA_HUMAN (113-296): 5.54e-30: 121: 20.86
+	Dm
		1250382 Q9VMN9_DROME (144-291): 1.74e-13: 72.2: 14.72		Q8T603_DROME (32-279): 2.16e-33: 130: 12.90
+	Dm
		56438 Q9VMN9_DROME (144-291): 1.74e-13: 72.2: 14.72		A1ZBY3_DROME (32-279): 2.2e-33: 130: 12.90
+	Mm
		1149039 CNTN4_MOUSE (17-265): 3.1e-30: 121: 19.38		CNTN4_MOUSE (4-389): 1.73e-11: 68.5: 11.11
+	Hs
		299597 LRIG2_HUMAN (8-144): 1.61e-11: 66.7: 16.79		BTNL2_HUMAN (32-275): 1.61e-22: 101: 16.67
+	Dm
		1370928 Q9VMN9_DROME (144-291): 1.74e-13: 72.2: 14.72		Q9VMN9_DROME (31-248): 9.36e-20: 93.2: 15.46