HitPredict

Interactor 1: CEA21 (Q3KPI0)
Carcinoembryonic antigen-related cell adhesion molecule 21
Gene: CEACAM21

Interactor 2: ULBP3 (Q9BZM4)
UL16-binding protein 3 (ALCAN-gamma) (NKG2D ligand 3) (N2DL-3) (NKG2DL3) (Retinoic acid early transcript 1N)
Gene: ULBP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	MHC_I~V-set
Common GO terms	GO:0009897 - external side of plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 244
+	Hs
		382443 CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00		HLAA_HUMAN (8-240): 1.83e-116: 338: 23.21
+	Hs
		488246 CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00		HLAC_HUMAN (7-240): 7.71e-110: 322: 21.85
+	Hs
		1108807 CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00		ULBP1_HUMAN (1-243): 2.59e-106: 308: 54.10
+	Hs
		673961 CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00		HLAF_HUMAN (9-240): 1.97e-97: 289: 21.61
+	Hs
		1108801 CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00		HMR1_HUMAN (11-240): 2.96e-92: 276: 24.35
+	Hs
		533162 LRIG1_HUMAN (5-283): 4.14e-39: 147: 16.14		HLAE_HUMAN (25-240): 5.91e-104: 306: 24.55
+	Hs
		382329 VGFR3_HUMAN (38-238): 2.33e-16: 81.3: 16.75		HLAA_HUMAN (8-240): 1.83e-116: 338: 23.21
+	Hs
		299553 LRIG2_HUMAN (8-144): 1.61e-11: 66.7: 16.79		HLAG_HUMAN (8-241): 3.14e-114: 332: 21.43