HitPredict

Interactor 1: ASTRB (Q3KR37)
Protein Aster-B (GRAM domain-containing protein 1B)
Gene: GRAMD1B

Interactor 2: TMX1 (Q9H3N1)
Thioredoxin-related transmembrane protein 1 (Protein disulfide-isomerase TMX1) (EC 5.3.4.1) (Thioredoxin domain-containing protein 1) (Transmembrane Trx-related protein)
Gene: TMX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 738 Hs			1 280
+	Hs
		1287028 ASTRA_HUMAN (9-725): 0: 783: 46.78		TMX1_HUMAN (1-280): 1.13e-79: 243: 100.00
+	Hs
		1287016 ASTRA_HUMAN (9-725): 0: 783: 46.78		ERP44_HUMAN (1-161): 1.35e-38: 141: 23.12
+	Hs
		531943 ASTRA_HUMAN (9-725): 0: 783: 46.78		PDIA4_HUMAN (119-266): 7.26e-15: 76.3: 9.68
+	Hs
		1220451 ASTRA_HUMAN (9-725): 0: 783: 46.78		DJC10_HUMAN (64-264): 2.26e-14: 74.8: 10.95
+	Hs
		1223510 ASTRC_HUMAN (21-719): 0: 547: 38.19		TMX1_HUMAN (1-280): 1.13e-79: 243: 100.00
+	Hs
		1293578 GRM2B_HUMAN (22-342): 7.24e-72: 242: 22.80		TMX1_HUMAN (1-280): 1.13e-79: 243: 100.00