HitPredict

Interactor 1: SP6 (Q3SY56)
Transcription factor Sp6 (Krueppel-like factor 14)
Gene: SP6

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19088080
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Hs			1 488
+	Hs
		177338 SP7_HUMAN (28-374): 6.39e-99: 301: 37.93		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		970932 SP3_HUMAN (225-340): 1.89e-45: 168: 68.97		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1158943 ZFP1_HUMAN (199-375): 4.96e-47: 166: 17.51		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Mm
		250993 SP3_MOUSE (225-340): 7.52e-46: 169: 68.97		HDAC2_MOUSE (1-488): 0: 704: 99.39
+	Hs
		435149 SP1_HUMAN (184-375): 1.85e-40: 154: 45.13		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1046724 KLF5_HUMAN (249-337): 4.73e-26: 110: 58.43		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Mm
		140208 SP3_MOUSE (225-340): 7.52e-46: 169: 68.97		HDAC1_MOUSE (1-443): 0: 645: 90.29
+	Hs
		970913 SP3_HUMAN (225-340): 1.89e-45: 168: 68.97		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1193248 ZSCA2_HUMAN (20-370): 1.13e-136: 404: 12.60		HDAC8_HUMAN (33-372): 1.01e-137: 403: 43.40
+	Mm
		140212 SP1_MOUSE (198-375): 3.96e-41: 155: 48.32		HDAC1_MOUSE (1-443): 0: 645: 90.29
+	Hs
		435085 SP1_HUMAN (184-375): 1.85e-40: 154: 45.13		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Mm
		140295 Q8BPQ2_MOUSE (245-336): 3.06e-26: 108: 56.52		HDAC1_MOUSE (1-443): 0: 645: 90.29
+	Hs
		1038360 KLF5_HUMAN (249-337): 4.73e-26: 110: 58.43		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		157899 KLF11_HUMAN (256-341): 9.49e-26: 110: 61.63		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		177170 SP1_HUMAN (184-375): 1.85e-40: 154: 45.13		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Mm
		292670 SP1_MOUSE (198-375): 3.96e-41: 155: 48.32		Q9JM08_MOUSE (10-431): 0: 568: 58.02
+	Hs
		177364 KLF6_HUMAN (245-336): 3.48e-27: 110: 56.52		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Mm
		1207125 Q8BPQ2_MOUSE (245-336): 3.06e-26: 108: 56.52		Q9JM08_MOUSE (10-431): 0: 568: 58.02
+	Hs
		599074 ZNF10_HUMAN (287-375): 3.48e-31: 126: 16.38		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		1260184 KLF16_HUMAN (254-338): 4.48e-27: 109: 61.18		HDAC7_HUMAN (29-280): 1.96e-23: 106: 26.37