HitPredict

Interactor 1: STING (Q3TBT3)
Stimulator of interferon genes protein (mSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (MMITA) (Transmembrane protein 173)
Gene: Sting1

Interactor 2: CERS2 (Q924Z4)
Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (Sphingosine N-acyltransferase CERS2) (EC 2.3.1.24) (Translocating chain-associating membrane protein homolog 3) (TRAM homolog 3) (Tumor metastasis-suppressor gene 1 protein) (Very-long-chain ceramide synthase CERS2) (EC 2.3.1.297)
Gene: CERS2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32554809
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 378 Mm			1 380
+	Mm
		1111556 STING_MOUSE (1-378): 0: 595: 100.00		CERS5_MOUSE (2-340): 1.94e-138: 402: 42.23
+	Mm
		1111055 STING_MOUSE (1-378): 0: 595: 100.00		CERS6_MOUSE (8-337): 1.82e-128: 375: 42.30
+	Mm
		1111361 STING_MOUSE (1-378): 0: 595: 100.00		TRAM2_MOUSE (120-368): 1.35e-66: 216: 18.90
+	Mm
		1111268 STING_MOUSE (1-378): 0: 595: 100.00		TRAM1_MOUSE (121-368): 6.78e-64: 210: 17.86