HitPredict

Interactor 1: I6L9F6 (I6L9F6)
NEFL protein
Gene: NEFL

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 284 Hs			1 247
+	Hs
		422160 NFL_HUMAN (1-283): 2.55e-65: 214: 64.36		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		904437 KRT85_HUMAN (1-282): 1.82e-64: 211: 19.73		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		905163 KRT82_HUMAN (17-282): 5.56e-64: 210: 19.42		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Mm
		910243 K22O_MOUSE (52-284): 2.97e-56: 192: 22.89		1433E_MOUSE (1-244): 2.02e-141: 398: 63.53
+	Hs
		904944 KRT35_HUMAN (2-281): 2.96e-56: 189: 17.25		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Mm
		440264 NFL_MOUSE (1-283): 1.78e-65: 215: 63.40		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Hs
		443445 VIME_HUMAN (34-283): 4.41e-20: 91.3: 28.15		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		443441 VIME_HUMAN (34-283): 4.41e-20: 91.3: 28.15		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Mm
		804937 AINX_MOUSE (136-283): 6.89e-18: 85.1: 37.18		1433E_MOUSE (1-244): 2.02e-141: 398: 63.53
+	Hs
		909606 AINX_HUMAN (136-283): 5.73e-18: 85.1: 37.82		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		904613 AINX_HUMAN (136-283): 5.73e-18: 85.1: 37.82		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		443469 VIME_HUMAN (34-283): 4.41e-20: 91.3: 28.15		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		982050 AINX_HUMAN (136-283): 5.73e-18: 85.1: 37.82		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Mm
		440289 NFM_MOUSE (27-283): 3.87e-22: 97.8: 30.79		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Hs
		443356 VIME_HUMAN (34-283): 4.41e-20: 91.3: 28.15		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		443452 VIME_HUMAN (34-283): 4.41e-20: 91.3: 28.15		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		443346 VIME_HUMAN (34-283): 4.41e-20: 91.3: 28.15		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		646928 AINX_HUMAN (136-283): 5.73e-18: 85.1: 37.82		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		443357 VIME_HUMAN (34-283): 4.41e-20: 91.3: 28.15		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		684061 AINX_HUMAN (136-283): 5.73e-18: 85.1: 37.82		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16