HitPredict

Interactor 1: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Interactor 2: LAR4B (Q92615)
La-related protein 4B (La ribonucleoprotein domain family member 4B) (La ribonucleoprotein domain family member 5) (La-related protein 5)
Gene: LARP4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 282 Hs			1 738
+	Hs
		1102038 PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49		LAR4B_HUMAN (1-738): 0: 654: 100.00
+	Hs
		550388 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		LAR4B_HUMAN (1-738): 0: 654: 100.00
+	Hs
		550338 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		LARP4_HUMAN (50-738): 1.66e-168: 503: 36.78
+	Hs
		1111795 TRA2A_HUMAN (1-253): 2.2e-47: 161: 100.00		LARP1_HUMAN (31-367): 7.94e-52: 197: 16.19
+	Hs
		1101996 PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49		LARP1_HUMAN (31-367): 7.94e-52: 197: 16.19
+	Hs
		550331 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		LARP1_HUMAN (31-367): 7.94e-52: 197: 16.19
+	Hs
		1111787 TRA2A_HUMAN (1-253): 2.2e-47: 161: 100.00		LARP7_HUMAN (154-461): 2.71e-44: 170: 15.43
+	Dm
		1303437 Q8IMX4_DROME (27-278): 4.2e-17: 82.5: 11.38		LAR4_DROME (105-472): 1.16e-68: 248: 34.38
+	Hs
		431115 PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49		LA_HUMAN (156-519): 9.61e-49: 179: 10.15
+	Hs
		988131 TRA2B_HUMAN (1-257): 9.05e-43: 149: 55.25		LARP7_HUMAN (154-461): 2.71e-44: 170: 15.43
+	Hs
		1101980 PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49		LARP7_HUMAN (154-461): 2.71e-44: 170: 15.43
+	Hs
		550310 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		LARP7_HUMAN (154-461): 2.71e-44: 170: 15.43
+	Hs
		1194132 PAP1L_HUMAN (1-272): 3.52e-37: 140: 14.59		LARP7_HUMAN (154-461): 2.71e-44: 170: 15.43
+	Hs
		1194374 PABP3_HUMAN (1-267): 7.72e-34: 131: 13.77		LARP7_HUMAN (154-461): 2.71e-44: 170: 15.43
+	Hs
		1111792 TRA2A_HUMAN (1-253): 2.2e-47: 161: 100.00		LAR1B_HUMAN (114-266): 3.25e-28: 123: 16.99
+	Hs
		1194271 MSI2H_HUMAN (100-256): 4.46e-23: 98.3: 20.25		LARP7_HUMAN (154-461): 2.71e-44: 170: 15.43
+	Hs
		550323 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		LAR1B_HUMAN (114-266): 3.25e-28: 123: 16.99
+	At
		306158 PABP8_ARATH (1-119): 3.75e-11: 65.1: 5.04		LRP6B_ARATH (64-365): 2.43e-54: 197: 14.54
+	At
		306156 PABP2_ARATH (1-119): 1.61e-09: 60.1: 9.24		LRP6B_ARATH (64-365): 2.43e-54: 197: 14.54
+	At
		842070 PABP2_ARATH (1-119): 1.61e-09: 60.1: 9.24		LRP6C_ARATH (107-315): 6.73e-51: 186: 16.10