HitPredict

Interactor 1: Q3TQ10 (Q3TQ10)
TSC complex subunit 2
Gene: Tsc2

Interactor 2: RHEB (Q921J2)
GTP-binding protein Rheb (Ras homolog enriched in brain) (EC 3.6.5.-)
Gene: RHEB

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30514904
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rap_GAP~Ras
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 237 Mm			1 184
+	Hs
		835062 TSC2_HUMAN (1-237): 8.21e-106: 337: 77.69		RHEB_HUMAN (1-184): 1.73e-93: 271: 98.91
+	Hs
		835037 TSC2_HUMAN (1-237): 8.21e-106: 337: 77.69		RAP1A_HUMAN (5-169): 2.45e-36: 126: 38.55
+	Hs
		914140 RGPA1_HUMAN (2-211): 6.93e-68: 228: 21.43		RB11A_HUMAN (4-180): 9.99e-78: 232: 30.34
+	Hs
		895128 RGPA1_HUMAN (2-211): 6.93e-68: 228: 21.43		RAB2A_HUMAN (1-173): 1.42e-76: 229: 31.03
+	Hs
		914099 RGPA2_HUMAN (2-198): 5.04e-65: 220: 23.35		RB11A_HUMAN (4-180): 9.99e-78: 232: 30.34
+	Hs
		506370 TSC2_HUMAN (1-237): 8.21e-106: 337: 77.69		RALA_HUMAN (8-166): 6.04e-31: 113: 35.22
+	Mm
		1193420 SI1L2_MOUSE (2-195): 4.48e-49: 174: 19.00		RHEB_MOUSE (1-184): 2.1e-93: 271: 100.00
+	Dm
		114693 M9PD17_DROME (3-195): 1.76e-59: 204: 38.97		RHEB_DROME (1-183): 9.26e-75: 224: 63.93
+	Dm
		1371386 Q9VW83_DROME (3-195): 1.76e-59: 204: 38.97		RHEB_DROME (1-183): 9.26e-75: 224: 63.93
+	Hs
		812872 RPGP1_HUMAN (3-196): 2.74e-53: 183: 21.89		RAP1B_HUMAN (5-184): 1.1e-37: 129: 38.04
+	Hs
		812875 RPGP1_HUMAN (3-196): 2.74e-53: 183: 21.89		RAP1A_HUMAN (5-169): 2.45e-36: 126: 38.55