Interactor 1: CBLB (Q3TTA7)
E3 ubiquitin-protein ligase CBL-B (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene b) (RING-type E3 ubiquitin transferase CBL-B) (SH3-binding protein CBL-B) (Signal transduction protein CBL-B)
Gene: CBLB

Interactor 2: CBLC (Q80XL1)
E3 ubiquitin-protein ligase CBL-C (EC 2.3.2.27) (RING-type E3 ubiquitin transferase CBL-C) (SH3-binding protein CBL-3) (SH3-binding protein CBL-C) (Signal transduction protein CBL-C)
Gene: CBLC

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 12842890
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cbl_N~Cbl_N, Cbl_N~Cbl_N2, Cbl_N~Cbl_N3, Cbl_N2~Cbl_N2, Cbl_N2~Cbl_N3
Common GO terms GO:0001784 - phosphotyrosine residue binding
GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0016567 - protein ubiquitination
and 5 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 982
Mm

1 496
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024