HitPredict

Interactor 1: I6L9I8 (I6L9I8)
EPN3 protein (Epsin 3)
Gene: EPN3

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UIM~ubiquitin
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 318 Hs			1 156
+	Hs
		924159 EPN3_HUMAN (1-311): 7.44e-139: 408: 95.57		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		924231 EPN1_HUMAN (1-304): 1.72e-115: 346: 57.69		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		924407 EPN3_HUMAN (1-311): 7.44e-139: 408: 95.57		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		307522 EPN2_HUMAN (1-305): 1.04e-103: 318: 48.13		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		475183 EPN3_HUMAN (1-311): 7.44e-139: 408: 95.57		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	Mm
		476910 EPN2_MOUSE (1-283): 3.55e-115: 346: 60.66		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Mm
		476869 EPN1_MOUSE (1-304): 6.14e-114: 343: 57.69		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Rn
		291394 EPN1_RAT (1-304): 6.21e-114: 343: 57.69		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Hs
		307523 EPN2_HUMAN (1-305): 1.04e-103: 318: 48.13		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	At
		1091714 EPN2_ARATH (2-305): 4.31e-97: 307: 32.90		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Dm
		1182371 Q7KU90_DROME (1-315): 1.66e-102: 320: 46.98		R9PY16_DROME (1-68): 7.11e-29: 108: 91.18