HitPredict

Interactor 1: CRTC2 (Q3U182)
CREB-regulated transcription coactivator 2 (Transducer of regulated cAMP response element-binding protein 2) (TORC-2) (Transducer of CREB protein 2)
Gene: CRTC2

Interactor 2: COP1 (Q9R1A8)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	17805301
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 692 Mm			1 733
+	Hs
		1120141 CRTC2_HUMAN (1-692): 1.27e-78: 266: 91.93		COP1_HUMAN (1-733): 0: 550: 97.54
+	Hs
		1281318 EP400_HUMAN (283-596): 9.68e-21: 100: 12.54		FBXW7_HUMAN (145-719): 9.98e-81: 273: 12.54
+	Hs
		1281391 PRR36_HUMAN (8-620): 2.91e-15: 82.2: 11.49		FBXW7_HUMAN (145-719): 9.98e-81: 273: 12.54
+	Hs
		302275 SC31A_HUMAN (194-557): 6.12e-11: 68.3: 11.20		WDR5_HUMAN (297-627): 1.36e-65: 222: 15.34
+	Hs
		903450 CIC_HUMAN (155-687): 1.07e-10: 67.6: 10.29		WDR5_HUMAN (297-627): 1.36e-65: 222: 15.34
+	Hs
		903374 KMT2C_HUMAN (200-686): 1.64e-10: 66.8: 8.13		WDR5_HUMAN (297-627): 1.36e-65: 222: 15.34
+	Mm
		903669 KMT2C_MOUSE (224-679): 1.75e-09: 63.6: 11.47		WDR5_MOUSE (297-627): 1.36e-65: 222: 15.34
+	Hs
		903345 Q86V38_HUMAN (24-578): 2.38e-09: 63: 9.98		WDR5_HUMAN (297-627): 1.36e-65: 222: 15.34
+	Hs
		869446 ATN1_HUMAN (106-684): 8.26e-09: 61: 14.89		WDR5_HUMAN (297-627): 1.36e-65: 222: 15.34
+	Hs
		1074805 CIC_HUMAN (155-687): 1.07e-10: 67.6: 10.29		TAF5_HUMAN (527-733): 2.97e-36: 148: 17.79
+	Hs
		1288242 EP400_HUMAN (283-596): 9.68e-21: 100: 12.54		SNR40_HUMAN (589-732): 4.4e-27: 115: 19.05
+	Hs
		131738 BCL9_HUMAN (73-677): 1.74e-19: 95.7: 12.97		SNR40_HUMAN (589-732): 4.4e-27: 115: 19.05
+	Ce
		953956 Q19371_CAEEL (280-537): 1.89e-23: 108: 17.44		LIN53_CAEEL (554-684): 1.48e-12: 72.1: 18.12
+	Hs
		869506 ATN1_HUMAN (106-684): 8.26e-09: 61: 14.89		SNR40_HUMAN (589-732): 4.4e-27: 115: 19.05
+	Ce
		557846 RPB1_CAEEL (184-565): 1.37e-21: 102: 15.91		LIN53_CAEEL (554-684): 1.48e-12: 72.1: 18.12
+	Hs
		1083349 EP400_HUMAN (283-596): 9.68e-21: 100: 12.54		RBBP7_HUMAN (478-631): 3.54e-12: 70.9: 29.34
+	Hs
		997936 CHD7_HUMAN (136-667): 5.85e-16: 84.5: 10.11		RBBP4_HUMAN (478-631): 1.5e-12: 72: 29.34
+	Hs
		997865 CIC_HUMAN (155-687): 1.07e-10: 67.6: 10.29		RBBP4_HUMAN (478-631): 1.5e-12: 72: 29.34
+	Hs
		1083355 CIC_HUMAN (155-687): 1.07e-10: 67.6: 10.29		RBBP7_HUMAN (478-631): 3.54e-12: 70.9: 29.34