HitPredict

Interactor 1: PHAG1 (Q3U1F9)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp)
Gene: Pag1

Interactor 2: NCK1 (Q99M51)
SH2/SH3 adapter protein Nck1 (Cytoplasmic protein Nck1) (NCK adapter protein 1) (Nck-1)
Gene: NCK1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	26512138
Identification Methods	affinity chromatography technology
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	PAG~SH2
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 429 Mm			1 377
+	Mm
		223013 PHAG1_MOUSE (1-429): 0: 785: 100.00		NCK2_MOUSE (1-376): 3.34e-90: 278: 67.19
+	Mm
		643088 PHAG1_MOUSE (1-429): 0: 785: 100.00		P85A_MOUSE (241-376): 2.56e-22: 100: 19.57
+	Mm
		763390 PHAG1_MOUSE (1-429): 0: 785: 100.00		FYN_MOUSE (6-130): 3.25e-22: 99.8: 21.26
+	Mm
		782848 PHAG1_MOUSE (1-429): 0: 785: 100.00		CSK_MOUSE (4-143): 8.51e-17: 83.3: 14.38
+	Mm
		1112191 PHAG1_MOUSE (1-429): 0: 785: 100.00		GRB2_MOUSE (3-58): 7.7e-17: 80.6: 28.57
+	Rn
		693647 PHAG1_RAT (1-429): 0: 764: 89.51		CSK_RAT (4-143): 8.51e-17: 83.3: 14.38
+	Hs
		412375 PHAG1_HUMAN (1-429): 0: 705: 78.21		FYN_HUMAN (6-130): 3.47e-22: 99.8: 21.26
+	Hs
		789135 PHAG1_HUMAN (1-429): 0: 705: 78.21		FRK_HUMAN (3-150): 3.51e-19: 91: 17.20
+	Hs
		523175 PHAG1_HUMAN (1-429): 0: 705: 78.21		SRC_HUMAN (6-130): 5.78e-19: 90.1: 21.26
+	Hs
		782829 PHAG1_HUMAN (1-429): 0: 705: 78.21		CSK_HUMAN (4-143): 8.06e-17: 83.7: 14.38
+	Hs
		924899 PHAG1_HUMAN (1-429): 0: 705: 78.21		GRB2_HUMAN (3-58): 7.33e-17: 80.6: 28.57