HitPredict

Interactor 1: DDB1 (Q3U1J4)
DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)
Gene: DDB1

Interactor 2: WDR81 (Q5ND34)
WD repeat-containing protein 81
Gene: WDR81

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34161765
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1140 Mm			1 1934
+	Hs
		903254 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5_HUMAN (1466-1806): 8.49e-68: 234: 14.93
+	Hs
		1082263 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5B_HUMAN (1474-1806): 4.25e-65: 226: 12.89
+	Hs
		1082327 DDB1_HUMAN (1-1140): 0: 1445: 99.65		SNR40_HUMAN (1495-1846): 2.1e-51: 188: 17.34
+	Mm
		1112254 DDB1_MOUSE (1-1140): 0: 1446: 100.00		WDFY3_MOUSE (1671-1890): 7.52e-24: 112: 9.50
+	At
		95049 DDB1A_ARATH (2-1140): 0: 1254: 52.18		KTN82_ARATH (1633-1897): 2.7e-54: 211: 22.96
+	At
		95047 DDB1B_ARATH (3-1140): 0: 1248: 51.00		KTN82_ARATH (1633-1897): 2.7e-54: 211: 22.96
+	Hs
		1073094 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		FBXW7_HUMAN (1524-1840): 8.16e-61: 225: 17.96
+	Hs
		1073010 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		WDR81_HUMAN (1727-1933): 2.72e-22: 107: 13.64
+	Mm
		93178 SF3B3_MOUSE (3-1126): 0: 1095: 21.25		E9PV60_MOUSE (1742-1933): 2.3e-21: 104: 14.90
+	Sc
		744701 CFT1_YEAST (11-1125): 0: 673: 14.71		TAF5_YEAST (1600-1903): 1.79e-21: 104: 18.69
+	Hs
		1014154 CPSF1_HUMAN (4-527): 1.42e-116: 396: 16.01		NBEL2_HUMAN (1648-1932): 2.05e-20: 101: 15.86