HitPredict

Interactor 1: I7GPR1 (I7GPR1)
TRAF3 interacting protein 2
Gene: Traf3ip2

Interactor 2: TRAF5 (P70191)
TNF receptor-associated factor 5
Gene: TRAF5

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	23042150
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 555 Mm			1 558
+	Mm
		936209 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF5_MOUSE (1-558): 3.74e-153: 452: 100.00
+	Mm
		1141427 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF3_MOUSE (7-557): 3.31e-119: 365: 41.91
+	Hs
		129517 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF5_HUMAN (1-558): 1.55e-150: 445: 79.57
+	Mm
		761830 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF2_MOUSE (13-555): 4.65e-106: 329: 30.02
+	Mm
		111226 I7GPR1_MOUSE (1-555): 0: 1019: 100.00		TRAF6_MOUSE (21-552): 5.7e-82: 267: 23.05
+	Hs
		212251 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF3_HUMAN (7-557): 2.72e-120: 368: 41.65
+	Mm
		936263 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF6_MOUSE (21-552): 5.7e-82: 267: 23.05
+	Mm
		936253 Q8C0E5_MOUSE (1-555): 0: 1014: 98.92		TRAF6_MOUSE (21-552): 5.7e-82: 267: 23.05
+	Hs
		212248 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF2_HUMAN (13-555): 4e-106: 329: 28.57
+	Mm
		1142553 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF4_MOUSE (29-552): 1.39e-65: 222: 21.35
+	Hs
		212277 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF6_HUMAN (21-552): 3.48e-80: 262: 22.86
+	Hs
		212249 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF1_HUMAN (161-553): 1.45e-80: 260: 31.49