Interactor 1: J3KN53 (J3KN53)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27)
Gene: MDM2

Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 25609649
Identification Methods tandem affinity purification
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002039 - p53 binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0043066 - negative regulation of apoptotic process
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 466
Hs

1 393
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024