HitPredict

Interactor 1: SNX27 (Q3UHD6)
Sorting nexin-27
Gene: SNX27

Interactor 2: ANS1B (Q8BIZ1)
Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1)
Gene: Anks1b

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	31388001
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PDZ~PID, PDZ~SAM_1
Common GO terms	GO:0005829 - cytosol GO:0098685 - Schaffer collateral - CA1 synapse GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 539 Mm			1 1259
+	Mm
		1143393 DLG4_MOUSE (11-136): 3.63e-24: 108: 24.41		ANS1B_MOUSE (1-1259): 0: 938: 100.00
+	Hs
		1296957 SNX27_HUMAN (1-539): 0: 574: 98.34		ANR50_HUMAN (2-859): 6.31e-88: 315: 16.63
+	Hs
		166999 SNX27_HUMAN (1-539): 0: 574: 98.34		ANR28_HUMAN (2-500): 1.11e-71: 262: 17.60
+	Hs
		1268489 SNX27_HUMAN (1-539): 0: 574: 98.34		ANS1A_HUMAN (1-980): 4.87e-69: 255: 29.07
+	Hs
		1296956 SNX27_HUMAN (1-539): 0: 574: 98.34		KDIS_HUMAN (33-390): 1.49e-65: 246: 19.18
+	Hs
		1296915 SNX27_HUMAN (1-539): 0: 574: 98.34		TANC2_HUMAN (104-1028): 3.1e-30: 132: 12.41
+	Dm
		113386 M9NFI9_DROME (38-332): 9.59e-37: 148: 14.38		Q9VCM6_DROME (1-1190): 9.4e-118: 400: 24.49
+	Mm
		1143409 DLG4_MOUSE (11-136): 3.63e-24: 108: 24.41		Q8BZM2_MOUSE (800-1259): 4.26e-141: 438: 98.04
+	Hs
		167037 NEB1_HUMAN (38-411): 2.97e-42: 164: 14.36		ANR28_HUMAN (2-500): 1.11e-71: 262: 17.60
+	Mm
		1160646 SHAN2_MOUSE (41-145): 3.63e-32: 134: 39.05		CSKI1_MOUSE (1-311): 4.53e-78: 285: 37.19
+	Mm
		292489 LIN7C_MOUSE (33-162): 3.39e-28: 113: 28.24		CSKI1_MOUSE (1-311): 4.53e-78: 285: 37.19
+	Mm
		103604 NEB2_MOUSE (38-313): 3.28e-29: 124: 15.87		ANK3_MOUSE (8-1075): 2.51e-70: 262: 12.20
+	Hs
		310110 RPGF2_HUMAN (23-315): 5.86e-35: 142: 17.33		TNKS1_HUMAN (2-570): 8.9e-62: 234: 15.41
+	Hs
		1021414 RHG21_HUMAN (1-166): 4.71e-34: 139: 22.80		ANK3_HUMAN (5-322): 1.58e-61: 234: 21.75
+	Mm
		103602 DLG4_MOUSE (11-136): 3.63e-24: 108: 24.41		ANK3_MOUSE (8-1075): 2.51e-70: 262: 12.20
+	Dm
		113372 M9NFI9_DROME (38-332): 9.59e-37: 148: 14.38		TNKS_DROME (2-595): 8.54e-56: 214: 15.08
+	Mm
		887083 DLG4_MOUSE (11-136): 3.63e-24: 108: 24.41		ANS1A_MOUSE (1-980): 2.5e-66: 247: 27.80
+	Dm
		113219 M9NFI9_DROME (38-332): 9.59e-37: 148: 14.38		Q7KU92_DROME (86-1067): 7.84e-53: 206: 11.64
+	Mm
		56844 DLG4_MOUSE (11-136): 3.63e-24: 108: 24.41		TANC2_MOUSE (104-1050): 2.06e-29: 129: 11.75
+	Mm
		1163989 NEB2_MOUSE (38-313): 3.28e-29: 124: 15.87		ANK2_MOUSE (66-258): 3.34e-10: 67: 30.05