Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1
Interactor 2: FBX22 (Q8NEZ5)
F-box only protein 22 (F-box protein FBX22p44)
Gene: FBXO22
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.970 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29103612, 32249768, 37028429, 37837399, 21145461, 29945959, 31217475, 36774506, 38965383, 22268729 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cullin~F-box |
| Common GO terms | GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
