Interactor 1: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Interactor 2: RPGF4 (Q9EQZ6)
Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII)
Gene: Rapgef4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 28706196
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~RasGEF, Ras~RasGEF_N
Common GO terms GO:0005829 - cytosol
GO:0030425 - dendrite
GO:0044877 - protein-containing complex binding
GO:0098978 - glutamatergic synapse
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1186
Mm

1 1011
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Last updated: 15 Jul 2024