HitPredict

Interactor 1: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Interactor 2: HOME1 (Q9Z2Y3)
Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)
Gene: Homer1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28671696, 28706196
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030425 - dendrite GO:0044877 - protein-containing complex binding GO:0098794 - postsynapse GO:0098978 - glutamatergic synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1186 Mm			1 366
+	Rn
		1208447 AGAP2_RAT (1-1186): 0: 1019: 99.07		HOME1_RAT (1-366): 8.35e-85: 263: 98.09
+	Mm
		1112657 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		HOME2_MOUSE (1-362): 7.54e-76: 239: 51.11
+	Rn
		292330 AGAP2_RAT (1-1186): 0: 1019: 99.07		HOME2_RAT (1-362): 1.54e-75: 239: 50.83
+	Hs
		1205719 AGAP2_HUMAN (1-1147): 0: 987: 94.10		HOME1_HUMAN (1-366): 4.29e-83: 258: 94.81
+	Mm
		93500 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		E9Q4F9_MOUSE (65-362): 1.29e-39: 144: 43.62
+	Mm
		975398 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		ENAH_MOUSE (1-182): 5.83e-33: 132: 22.40