Interactor 1: MET14 (Q3UIK4)
N6-adenosine-methyltransferase non-catalytic subunit (Methyltransferase-like protein 14)
Gene: Mettl14

Interactor 2: MTA70 (Q8C3P7)
N6-adenosine-methyltransferase subunit METTL3 (EC 2.1.1.348) (Methyltransferase-like protein 3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70)
Gene: Mettl3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24394384
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MT-A70~MT-A70
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0001510 - RNA methylation
GO:0001734 - mRNA m(6)A methyltransferase activity
GO:0003729 - mRNA binding
GO:0005634 - nucleus
and 8 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 456
Mm

1 580
+ Hs
+ Dm
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024