HitPredict

Interactor 1: Q3UJF1 (Q3UJF1)
Histone deacetylase (EC 3.5.1.98)
Gene: Hdac5

Interactor 2: FBW1A (Q3ULA2)
F-box/WD repeat-containing protein 1A (Beta-TrCP protein E3RS-IkappaB) (Beta-transducin repeat-containing protein) (Beta-TrCP) (E3RSIkappaB) (mE3RS-IkappaB) (F-box and WD repeats protein beta-TrCP) (HOS) (Ubiquitin ligase FWD1) (pIkappaB-E3 receptor subunit)
Gene: Btrc

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31040226
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1115 Mm			1 605
+	Mm
		1112937 HDAC5_MOUSE (1-1115): 0: 788: 99.28		FBW1A_MOUSE (1-605): 0: 582: 100.00
+	Mm
		1112755 Q3UJF1_MOUSE (1-1115): 0: 796: 100.00		FBW1B_MOUSE (110-605): 4.45e-147: 437: 87.50
+	Mm
		1131319 HDAC5_MOUSE (1-1115): 0: 788: 99.28		FBW1B_MOUSE (110-605): 4.45e-147: 437: 87.50
+	Hs
		903610 HDAC5_HUMAN (1-1115): 0: 760: 94.49		WDR5_HUMAN (458-605): 7.01e-38: 144: 25.33
+	Hs
		245649 HDAC5_HUMAN (1-1115): 0: 760: 94.49		TBL1X_HUMAN (501-605): 1.66e-14: 78.5: 19.13
+	Hs
		1318188 HDAC5_HUMAN (1-1115): 0: 760: 94.49		TBL1R_HUMAN (501-605): 2.18e-14: 78.1: 16.67
+	Hs
		245584 HDAC4_HUMAN (3-1095): 0: 697: 55.51		TBL1X_HUMAN (501-605): 1.66e-14: 78.5: 19.13
+	Hs
		880817 HDAC4_HUMAN (3-1095): 0: 697: 55.51		TBL1R_HUMAN (501-605): 2.18e-14: 78.1: 16.67
+	Hs
		1260173 HDAC7_HUMAN (112-1115): 1.57e-169: 526: 40.82		FBXW7_HUMAN (409-603): 5.92e-53: 194: 31.63
+	Hs
		1270358 HDAC2_HUMAN (673-1112): 2.75e-149: 457: 21.01		FBXW7_HUMAN (409-603): 5.92e-53: 194: 31.63
+	Hs
		903202 HDAC1_HUMAN (666-1072): 2.18e-153: 467: 21.70		WDR5_HUMAN (458-605): 7.01e-38: 144: 25.33
+	Hs
		245622 HDAC7_HUMAN (112-1115): 1.57e-169: 526: 40.82		TBL1X_HUMAN (501-605): 1.66e-14: 78.5: 19.13
+	Hs
		1260185 HDAC7_HUMAN (112-1115): 1.57e-169: 526: 40.82		TBL1R_HUMAN (501-605): 2.18e-14: 78.1: 16.67
+	Hs
		903404 HDAC2_HUMAN (673-1112): 2.75e-149: 457: 21.01		WDR5_HUMAN (458-605): 7.01e-38: 144: 25.33
+	Hs
		177249 HDAC3_HUMAN (673-1112): 1.85e-147: 450: 21.04		WDR5_HUMAN (458-605): 7.01e-38: 144: 25.33
+	Hs
		245600 HDAC1_HUMAN (666-1072): 2.18e-153: 467: 21.70		TBL1X_HUMAN (501-605): 1.66e-14: 78.5: 19.13
+	Hs
		1038686 HDAC1_HUMAN (666-1072): 2.18e-153: 467: 21.70		TBL1R_HUMAN (501-605): 2.18e-14: 78.1: 16.67
+	Hs
		245623 HDAC2_HUMAN (673-1112): 2.75e-149: 457: 21.01		TBL1X_HUMAN (501-605): 1.66e-14: 78.5: 19.13
+	Hs
		1270423 HDAC2_HUMAN (673-1112): 2.75e-149: 457: 21.01		TBL1R_HUMAN (501-605): 2.18e-14: 78.1: 16.67
+	Hs
		177148 HDAC3_HUMAN (673-1112): 1.85e-147: 450: 21.04		TBL1X_HUMAN (501-605): 1.66e-14: 78.5: 19.13