Interactor 1: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2
Interactor 2: ELOB (Q15370)
Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2)
Gene: ELOB
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.978 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31253590, 24981860, 12048197, 30166453, 11384984, 18173839, 15966899, 12149480, 21145461, 9122164, 15601820, 24076655, 19327355 |
| Identification Methods | affinity chromatography technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cullin~ubiquitin, Cullin_Nedd8~ubiquitin |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0031462 - Cul2-RING ubiquitin ligase complex GO:0031625 - ubiquitin protein ligase binding |
| Homologous interactions | 4 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025