HitPredict

Interactor 1: SRBS2 (Q3UTJ2)
Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2)
Gene: Sorbs2

Interactor 2: VINC (Q64727)
Vinculin (Metavinculin)
Gene: Vcl

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20886612
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0030018 - Z disc
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1180 Mm			1 1066
+	Hs
		298947 SRBS2_HUMAN (101-1180): 1.64e-167: 527: 86.47		VINC_HUMAN (1-1066): 0: 802: 90.56
+	Hs
		575737 SPTN1_HUMAN (461-1072): 2.69e-61: 233: 15.64		VINC_HUMAN (1-1066): 0: 802: 90.56
+	Hs
		282306 NEBL_HUMAN (492-1180): 1.97e-51: 199: 13.11		VINC_HUMAN (1-1066): 0: 802: 90.56
+	Hs
		235472 VINEX_HUMAN (723-1180): 4.09e-50: 191: 29.01		VINC_HUMAN (1-1066): 0: 802: 90.56
+	Hs
		575836 SRBS1_HUMAN (790-1000): 5.36e-12: 72.7: 14.02		VINC_HUMAN (1-1066): 0: 802: 90.56
+	Hs
		298955 SRBS2_HUMAN (101-1180): 1.64e-167: 527: 86.47		CTNA1_HUMAN (5-907): 6.98e-72: 259: 15.33
+	Ce
		104695 SRBS1_CAEEL (1017-1180): 3.54e-15: 82.8: 26.83		VINC_CAEEL (1-1064): 0: 654: 29.87
+	Hs
		282311 NEBL_HUMAN (492-1180): 1.97e-51: 199: 13.11		CTNA1_HUMAN (5-907): 6.98e-72: 259: 15.33
+	Dm
		2230 A0A0B4K6W0_DROME (191-1180): 2.27e-18: 93.7: 9.31		VINC_DROME (1-713): 4.27e-77: 275: 32.56
+	Dm
		52981 A1Z866_DROME (749-1180): 1.02e-11: 71.3: 12.79		VINC_DROME (1-713): 4.27e-77: 275: 32.56
+	Dm
		220701 Q86P80_DROME (714-1180): 1.58e-11: 70.6: 12.47		VINC_DROME (1-713): 4.27e-77: 275: 32.56
+	Hs
		716762 SRBS1_HUMAN (790-1000): 5.36e-12: 72.7: 14.02		CTNA1_HUMAN (5-907): 6.98e-72: 259: 15.33
+	Dm
		54294 SPTCA_DROME (461-1001): 1.77e-50: 198: 12.99		A1Z9J2_DROME (256-1019): 8.99e-10: 65.4: 13.67