HitPredict

Interactor 1: GRM5 (Q3UVX5)
Metabotropic glutamate receptor 5 (mGluR5)
Gene: GRM5

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

The method score is based on:

Property	Details
Experiments	27507650, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007611 - learning or memory GO:0007612 - learning GO:0007626 - locomotory behavior and 6 others more... GO:0043005 - neuron projection GO:0043197 - dendritic spine GO:0045211 - postsynaptic membrane GO:0048170 - positive regulation of long-term neuronal synaptic plasticity GO:0050804 - modulation of chemical synaptic transmission GO:0098978 - glutamatergic synapse
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	1203
Mm

1	1730

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024