HitPredict

Interactor 1: J3KT38 (J3KT38)
Growth factor receptor bound protein 2
Gene: GRB2

Interactor 2: NCF1 (P14598)
Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)
Gene: NCF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	30833792
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	SH2~SH3_1, NECFESHC~SH3_1, SH3_1~p47_phox_C, SH3_1~SH3_1
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 110 Hs			1 390
+	Hs
		433732 LYN_HUMAN (3-110): 8.42e-31: 115: 39.83		MYO1E_HUMAN (3-283): 4.56e-53: 191: 15.20
+	Hs
		411986 FYN_HUMAN (4-110): 9e-33: 121: 37.29		NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16
+	Hs
		433350 YES_HUMAN (4-110): 3.13e-32: 119: 34.75		SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67
+	Mm
		763403 FYN_MOUSE (4-110): 9.95e-33: 120: 37.29		NCK1_MOUSE (130-350): 2.3e-33: 129: 17.16
+	Hs
		337337 ABL1_HUMAN (4-110): 7.27e-31: 116: 36.94		NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16
+	Hs
		522981 SRC_HUMAN (4-110): 2.8e-31: 116: 34.75		SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67
+	Hs
		412328 FYN_HUMAN (4-110): 9e-33: 121: 37.29		SH3G2_HUMAN (6-211): 5.16e-32: 125: 10.68
+	Mm
		337637 ABL1_MOUSE (4-110): 6.6e-31: 116: 36.94		NCK1_MOUSE (130-350): 2.3e-33: 129: 17.16
+	Hs
		298944 ABL1_HUMAN (4-110): 7.27e-31: 116: 36.94		SRBS2_HUMAN (163-283): 1.9e-20: 95.7: 21.15
+	Hs
		412329 FYN_HUMAN (4-110): 9e-33: 121: 37.29		SH3G3_HUMAN (222-285): 2.65e-18: 87.1: 12.50
+	Hs
		235462 ABL1_HUMAN (4-110): 7.27e-31: 116: 36.94		VINEX_HUMAN (85-388): 1.86e-14: 77: 12.95
+	Hs
		433807 LYN_HUMAN (3-110): 8.42e-31: 115: 39.83		SH319_HUMAN (81-282): 8.99e-15: 77.9: 17.83
+	Hs
		433781 LYN_HUMAN (3-110): 8.42e-31: 115: 39.83		ITSN1_HUMAN (54-227): 2.01e-11: 67.7: 12.16
+	Hs
		412296 FYN_HUMAN (4-110): 9e-33: 121: 37.29		SH3K1_HUMAN (232-302): 3.59e-09: 60.6: 21.13
+	Hs
		454842 FGR_HUMAN (4-110): 7.86e-33: 121: 39.83		SH3K1_HUMAN (232-302): 3.59e-09: 60.6: 21.13
+	Hs
		523022 SRC_HUMAN (4-110): 2.8e-31: 116: 34.75		SPD2A_HUMAN (206-381): 1.55e-10: 65.1: 20.00
+	Hs
		411817 LCK_HUMAN (3-110): 1.4e-32: 120: 35.59		SH3K1_HUMAN (232-302): 3.59e-09: 60.6: 21.13
+	Hs
		442869 HCK_HUMAN (3-110): 9.51e-33: 120: 34.75		SH3K1_HUMAN (232-302): 3.59e-09: 60.6: 21.13
+	Hs
		337526 ABL1_HUMAN (4-110): 7.27e-31: 116: 36.94		SH3K1_HUMAN (232-302): 3.59e-09: 60.6: 21.13
+	Hs
		523104 SRC_HUMAN (4-110): 2.8e-31: 116: 34.75		SH3K1_HUMAN (232-302): 3.59e-09: 60.6: 21.13