HitPredict

Interactor 1: TBB8 (Q3ZCM7)
Tubulin beta-8 chain (Tubulin beta 8 class VIII)
Gene: TUBB8

Interactor 2: AURKC (Q9UQB9)
Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)
Gene: AURKC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 309
+	Hs
		160334 TBB5_HUMAN (1-429): 0: 720: 89.74		AURKA_HUMAN (1-299): 1.69e-135: 391: 64.90
+	Hs
		160504 TBB4B_HUMAN (1-427): 0: 719: 91.10		AURKA_HUMAN (1-299): 1.69e-135: 391: 64.90
+	Hs
		428041 TBB5_HUMAN (1-429): 0: 720: 89.74		AKT1_HUMAN (5-309): 8.7e-134: 389: 29.47
+	Hs
		681781 TBB4B_HUMAN (1-427): 0: 719: 91.10		AKT1_HUMAN (5-309): 8.7e-134: 389: 29.47
+	Hs
		428362 TBB5_HUMAN (1-429): 0: 720: 89.74		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Hs
		568654 TBB3_HUMAN (1-442): 0: 719: 86.43		KAPCA_HUMAN (6-308): 1.57e-133: 384: 29.75
+	Hs
		1046545 TBB2A_HUMAN (1-430): 0: 715: 90.00		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Dm
		445198 TBB3_DROME (1-443): 0: 709: 83.52		AKT1_DROME (3-309): 2.61e-132: 390: 29.32
+	Hs
		568659 TBB2A_HUMAN (1-430): 0: 715: 90.00		KAPCA_HUMAN (6-308): 1.57e-133: 384: 29.75
+	Dm
		1213355 Q8MST5_DROME (1-442): 0: 699: 83.33		AKT1_DROME (3-309): 2.61e-132: 390: 29.32
+	Dm
		332663 TBB1_DROME (1-429): 0: 718: 90.68		PLK4_DROME (39-293): 1.2e-57: 199: 38.76
+	Dm
		332650 TBB3_DROME (1-443): 0: 709: 83.52		PLK4_DROME (39-293): 1.2e-57: 199: 38.76