HitPredict

Interactor 1: ZACN (Q401N2)
Ligand-gated cation channel ZACN (Ligand-gated ion channel zinc-activated 1) (Ligand-gated ion-channel receptor L2) (Zinc-activated channel)
Gene: ZACN

Interactor 2: TMTC3 (Q6ZXV5)
Protein O-mannosyl-transferase TMTC3 (EC 2.4.1.109) (Protein SMILE) (Transmembrane O-mannosyltransferase targeting cadherins 3) (Transmembrane and tetratricopeptide repeat-containing 3)
Gene: TMTC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 915
+	Hs
		798506 ACHA4_HUMAN (29-364): 6.43e-129: 386: 18.10		TMTC3_HUMAN (1-915): 0: 839: 100.00
+	Hs
		802339 5HT3A_HUMAN (24-332): 3.32e-125: 372: 24.23		TMTC3_HUMAN (1-915): 0: 839: 100.00
+	Hs
		570851 ACHB2_HUMAN (24-410): 1.43e-122: 366: 16.71		TMTC3_HUMAN (1-915): 0: 839: 100.00
+	Hs
		677144 ACHB4_HUMAN (14-361): 8.96e-123: 366: 16.90		TMTC3_HUMAN (1-915): 0: 839: 100.00
+	Hs
		1173496 5HT3C_HUMAN (20-357): 1.11e-119: 357: 24.01		TMTC3_HUMAN (1-915): 0: 839: 100.00
+	Hs
		989624 ACHD_HUMAN (33-371): 2.33e-110: 335: 16.71		TMTC3_HUMAN (1-915): 0: 839: 100.00
+	Hs
		798490 ACHA4_HUMAN (29-364): 6.43e-129: 386: 18.10		TMTC4_HUMAN (705-894): 2.95e-18: 91.8: 13.57