HitPredict

Interactor 1: YAP1 (Q45VV3)
Transcriptional coactivator yorkie (Protein yorkie) (Transcriptional coactivator YAP1 homolog)
Gene: yki

Interactor 2: AJUBA (Q9VY77)
LIM domain-containing protein jub
Gene: jub

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20303269
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045572 - positive regulation of imaginal disc growth
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 395 Dm			1 728
+	Hs
		808647 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		ZYX_HUMAN (165-705): 7.93e-67: 232: 24.96
+	Hs
		1336088 SMUF1_HUMAN (52-380): 7.17e-74: 246: 19.90		PDLI7_HUMAN (337-710): 8.6e-31: 128: 14.97
+	Hs
		816282 SMUF1_HUMAN (52-380): 7.17e-74: 246: 19.90		LIMS1_HUMAN (459-635): 1.69e-30: 124: 21.35
+	Hs
		200166 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		TGFI1_HUMAN (240-707): 1.2e-42: 162: 17.93
+	Hs
		808955 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		PDLI7_HUMAN (337-710): 8.6e-31: 128: 14.97
+	Hs
		808847 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		PDLI5_HUMAN (123-635): 1.2e-29: 126: 13.12
+	Hs
		1050798 SMUF2_HUMAN (71-347): 2.39e-50: 182: 17.12		FHL2_HUMAN (603-728): 8.09e-28: 115: 25.40
+	Hs
		808640 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		TRIP6_HUMAN (162-632): 1.84e-21: 100: 13.43
+	Hs
		808849 YAP1_HUMAN (32-343): 1.31e-53: 187: 30.03		AJUBA_HUMAN (119-636): 1.3e-15: 82.5: 15.15
+	Mm
		1143674 ITCH_MOUSE (270-394): 9.48e-21: 96.4: 15.20		TGFI1_MOUSE (261-707): 4.24e-43: 164: 15.89
+	Hs
		200183 ITCH_HUMAN (158-394): 9.42e-21: 96.4: 12.66		TGFI1_HUMAN (240-707): 1.2e-42: 162: 17.93
+	Hs
		1327916 WWP1_HUMAN (41-285): 3.17e-27: 115: 15.00		PDLI7_HUMAN (337-710): 8.6e-31: 128: 14.97
+	Hs
		200165 NEDD4_HUMAN (268-382): 1.51e-10: 65.1: 18.85		TGFI1_HUMAN (240-707): 1.2e-42: 162: 17.93
+	Hs
		1076559 WWOX_HUMAN (237-353): 9.92e-32: 126: 33.33		TRIP6_HUMAN (162-632): 1.84e-21: 100: 13.43
+	Hs
		200184 NED4L_HUMAN (246-322): 8.24e-10: 62.8: 23.17		TGFI1_HUMAN (240-707): 1.2e-42: 162: 17.93
+	Hs
		125735 WWP2_HUMAN (128-393): 9.36e-19: 90.6: 11.94		PDLI7_HUMAN (337-710): 8.6e-31: 128: 14.97
+	Hs
		808283 NEDD4_HUMAN (268-382): 1.51e-10: 65.1: 18.85		PDLI7_HUMAN (337-710): 8.6e-31: 128: 14.97
+	Hs
		63209 SAV1_HUMAN (106-381): 1.87e-10: 64: 14.29		WTIP_HUMAN (581-720): 4.68e-20: 95.5: 27.40
+	Hs
		1294450 SAV1_HUMAN (106-381): 1.87e-10: 64: 14.29		AJUBA_HUMAN (119-636): 1.3e-15: 82.5: 15.15