HitPredict

Interactor 1: YQEF (Q46939)
Probable acetyl-CoA acetyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase)
Gene: YQEF

Interactor 2: YQEF (Q46939)
Probable acetyl-CoA acetyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase)
Gene: YQEF

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	24561554
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Thiolase_C~Thiolase_C, Thiolase_C~Thiolase_N, Thiolase_N~Thiolase_N
Common GO terms	GO:0003985 - acetyl-CoA C-acetyltransferase activity GO:0003988 - acetyl-CoA C-acyltransferase activity GO:0005829 - cytosol GO:0006635 - fatty acid beta-oxidation GO:0071271 - 1-butanol biosynthetic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 393 Ec			1 393
+	Hs
		623889 THIL_HUMAN (1-391): 9.52e-170: 482: 43.37		THIL_HUMAN (1-391): 9.52e-170: 482: 43.37
+	Hs
		623985 THIL_HUMAN (1-391): 9.52e-170: 482: 43.37		THIC_HUMAN (4-392): 8.52e-170: 481: 48.59
+	Hs
		1314565 THIC_HUMAN (4-392): 8.52e-170: 481: 48.59		THIC_HUMAN (4-392): 8.52e-170: 481: 48.59
+	At
		1248131 ACCT2_ARATH (2-390): 4.14e-168: 477: 44.25		ACCT2_ARATH (2-390): 4.14e-168: 477: 44.25
+	Sc
		783354 ERG10_YEAST (2-391): 6.05e-165: 469: 40.51		ERG10_YEAST (2-391): 6.05e-165: 469: 40.51
+	Sc
		653475 THIK_YEAST (2-392): 3.34e-138: 402: 36.02		THIK_YEAST (2-392): 3.34e-138: 402: 36.02
+	Mt
		111220 FADA5_MYCTU (1-391): 9.79e-126: 369: 38.46		FADA5_MYCTU (1-391): 9.79e-126: 369: 38.46