HitPredict

Interactor 1: Q494G8 (Q494G8)
F-box and leucine-rich repeat protein 6, isoform A (F-box and leucine-rich repeat protein 6, isoform B) (F-box and leucine-rich repeat protein 6, isoform C) (RE55062p)
Gene: Fbl6

Interactor 2: Q7KJ69 (Q7KJ69)
GEO01805p1 (IP02725p) (SKP1-related B) (SKPB)
Gene: SkpB

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	15575970
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	F-box-like~Skp1
Common GO terms	GO:0019005 - SCF ubiquitin ligase complex GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 720 Dm			1 161
+	Dm
		284980 Q494G8_DROME (1-720): 0: 708: 100.00		O77430_DROME (1-161): 1.33e-81: 239: 72.84
+	Dm
		285004 Q961T2_DROME (1-720): 0: 708: 99.86		O77430_DROME (1-161): 1.33e-81: 239: 72.84
+	Dm
		1180595 Q961T2_DROME (1-720): 0: 708: 99.86		Q7KJ69_DROME (1-161): 1.07e-78: 232: 100.00
+	Hs
		928987 FBXL6_HUMAN (221-707): 5.62e-85: 280: 29.42		SKP1_HUMAN (1-161): 1.52e-83: 244: 67.49
+	Mm
		1321913 FXL20_MOUSE (283-703): 1.88e-81: 267: 21.13		SKP1_MOUSE (1-161): 8.98e-84: 245: 67.49
+	Hs
		929033 FXL20_HUMAN (283-703): 1.42e-81: 267: 21.13		SKP1_HUMAN (1-161): 1.52e-83: 244: 67.49
+	Hs
		929008 FBX41_HUMAN (3-572): 7.39e-70: 247: 17.55		SKP1_HUMAN (1-161): 1.52e-83: 244: 67.49
+	Dm
		284989 Q8IGU5_DROME (287-683): 1.93e-55: 201: 18.01		O77430_DROME (1-161): 1.33e-81: 239: 72.84
+	Dm
		284994 Q8T0K1_DROME (283-683): 1.26e-55: 200: 18.08		O77430_DROME (1-161): 1.33e-81: 239: 72.84
+	Dm
		1180585 Q8IGU5_DROME (287-683): 1.93e-55: 201: 18.01		Q7KJ69_DROME (1-161): 1.07e-78: 232: 100.00
+	Dm
		1180588 Q8T0K1_DROME (283-683): 1.26e-55: 200: 18.08		Q7KJ69_DROME (1-161): 1.07e-78: 232: 100.00
+	At
		1107628 SKIP2_ARATH (247-701): 1.43e-59: 211: 19.26		SKP1A_ARATH (3-158): 8.15e-72: 214: 51.59
+	At
		221664 SKIP2_ARATH (247-701): 1.43e-59: 211: 19.26		ASK11_ARATH (3-158): 2.52e-71: 213: 46.80
+	At
		1322473 SKIP2_ARATH (247-701): 1.43e-59: 211: 19.26		SKP1B_ARATH (3-158): 1.25e-70: 211: 47.90
+	At
		137936 COI1_ARATH (295-715): 9.92e-52: 191: 13.43		SKP1A_ARATH (3-158): 8.15e-72: 214: 51.59
+	At
		137930 COI1_ARATH (295-715): 9.92e-52: 191: 13.43		ASK11_ARATH (3-158): 2.52e-71: 213: 46.80
+	At
		137946 COI1_ARATH (295-715): 9.92e-52: 191: 13.43		SKP1B_ARATH (3-158): 1.25e-70: 211: 47.90
+	At
		137931 COI1_ARATH (295-715): 9.92e-52: 191: 13.43		ASK12_ARATH (3-158): 4.9e-70: 210: 45.51
+	At
		1323395 FBL16_ARATH (291-700): 7.25e-49: 182: 19.28		SKP1B_ARATH (3-158): 1.25e-70: 211: 47.90
+	At
		1107609 FBX14_ARATH (181-612): 2.39e-38: 153: 15.65		SKP1A_ARATH (3-158): 8.15e-72: 214: 51.59