HitPredict

Interactor 1: K7EK07 (K7EK07)
Histone H3
Gene: H3-3B

Interactor 2: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Hs			1 560
+	Hs
		123231 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00
+	Mm
		223226 H33_MOUSE (1-132): 3.65e-57: 175: 100.00		CBX4_MOUSE (1-560): 5.82e-156: 459: 88.43
+	Hs
		935156 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		MPP8_HUMAN (6-431): 5.25e-87: 289: 13.72
+	Mm
		675496 H33_MOUSE (1-132): 3.65e-57: 175: 100.00		CBX2_MOUSE (2-559): 8.06e-91: 290: 22.85
+	Hs
		934768 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54
+	Mm
		952770 H33_MOUSE (1-132): 3.65e-57: 175: 100.00		CBX6_MOUSE (1-419): 2.28e-79: 257: 24.14
+	Hs
		316000 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19
+	Hs
		935387 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		CDYL_HUMAN (2-288): 4.47e-50: 183: 16.35
+	Hs
		934721 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94
+	Hs
		934987 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		CDYL2_HUMAN (9-215): 3.69e-40: 154: 16.22
+	Mm
		952771 H33_MOUSE (1-132): 3.65e-57: 175: 100.00		Q9DCC5_MOUSE (9-163): 8.8e-44: 155: 21.94
+	Hs
		800341 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		CBX5_HUMAN (11-171): 7.04e-41: 148: 19.88
+	Hs
		935237 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		SUV92_HUMAN (9-161): 9.77e-39: 148: 24.18
+	Mm
		952749 H33_MOUSE (1-132): 3.65e-57: 175: 100.00		CBX5_MOUSE (11-169): 3.2e-41: 149: 20.71
+	Hs
		327837 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		CBX7_HUMAN (1-250): 1.04e-38: 144: 30.71
+	Hs
		934657 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		CBX1_HUMAN (17-163): 1.89e-39: 144: 21.05
+	Mm
		935445 H31_MOUSE (1-132): 9.18e-58: 177: 96.21		CBX1_MOUSE (17-163): 1.89e-39: 144: 21.05
+	Hs
		203659 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		SUV91_HUMAN (4-154): 1.01e-32: 131: 21.15
+	Hs
		935259 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		CBX8_HUMAN (1-259): 7.16e-33: 131: 28.22
+	Mm
		952761 H33_MOUSE (1-132): 3.65e-57: 175: 100.00		CBX7_MOUSE (1-157): 5.25e-36: 133: 38.22