HitPredict

Interactor 1: K7EK07 (K7EK07)
Histone H3
Gene: H3-3B

Interactor 2: MSH6 (P52701)
DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160)
Gene: MSH6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Hs			1 1360
+	Hs
		855452 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		MSH6_HUMAN (1-1360): 0: 1486: 100.00
+	Hs
		855454 H33_HUMAN (1-132): 3.65e-57: 175: 100.00		MSH6_HUMAN (1-1360): 0: 1486: 100.00
+	Hs
		828177 CENPA_HUMAN (9-132): 4.69e-44: 142: 50.38		MSH6_HUMAN (1-1360): 0: 1486: 100.00
+	Hs
		594184 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		MSH3_HUMAN (173-1357): 0: 835: 22.16
+	Hs
		594185 H33_HUMAN (1-132): 3.65e-57: 175: 100.00		MSH3_HUMAN (173-1357): 0: 835: 22.16
+	Hs
		794232 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		MSH2_HUMAN (393-1360): 0: 824: 21.88
+	Hs
		794234 H33_HUMAN (1-132): 3.65e-57: 175: 100.00		MSH2_HUMAN (393-1360): 0: 824: 21.88
+	Sc
		902039 H3_YEAST (1-132): 9.86e-52: 161: 90.91		MSH6_YEAST (115-1347): 0: 821: 28.54
+	Hs
		594175 CENPA_HUMAN (9-132): 4.69e-44: 142: 50.38		MSH3_HUMAN (173-1357): 0: 835: 22.16
+	Sc
		639281 H3_YEAST (1-132): 9.86e-52: 161: 90.91		MSH2_YEAST (408-1354): 0: 725: 20.96
+	Hs
		935205 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		NSD3_HUMAN (4-390): 2.84e-86: 311: 19.51
+	Hs
		952607 H33_HUMAN (1-132): 3.65e-57: 175: 100.00		NSD3_HUMAN (4-390): 2.84e-86: 311: 19.51
+	Hs
		1086307 H31T_HUMAN (1-132): 8.77e-57: 174: 93.18		NSD3_HUMAN (4-390): 2.84e-86: 311: 19.51
+	Hs
		1157224 H3C_HUMAN (1-132): 2.17e-54: 168: 95.46		NSD3_HUMAN (4-390): 2.84e-86: 311: 19.51
+	Hs
		331780 H31_HUMAN (1-132): 9.18e-58: 177: 96.21		NSD2_HUMAN (4-411): 1.45e-80: 293: 17.44
+	Hs
		331787 H33_HUMAN (1-132): 3.65e-57: 175: 100.00		NSD2_HUMAN (4-411): 1.45e-80: 293: 17.44
+	Hs
		331823 H31T_HUMAN (1-132): 8.77e-57: 174: 93.18		NSD2_HUMAN (4-411): 1.45e-80: 293: 17.44
+	Hs
		331833 H32_HUMAN (1-132): 1.3e-56: 174: 96.97		NSD2_HUMAN (4-411): 1.45e-80: 293: 17.44
+	Hs
		828367 CENPA_HUMAN (9-132): 4.69e-44: 142: 50.38		NSD3_HUMAN (4-390): 2.84e-86: 311: 19.51
+	Hs
		331748 CENPA_HUMAN (9-132): 4.69e-44: 142: 50.38		NSD2_HUMAN (4-411): 1.45e-80: 293: 17.44