HitPredict

Interactor 1: Q49AR9 (Q49AR9)
ANKS1A protein
Gene: ANKS1A

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~PID, PDZ~SAM_1
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 570 Hs			1 728
+	Hs
		1252371 ANS1A_HUMAN (1-493): 8.68e-149: 458: 92.90		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252574 NUMBL_HUMAN (185-540): 2.44e-64: 223: 17.40		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		833629 NUMB_HUMAN (235-541): 6.02e-61: 214: 15.22		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Mm
		250665 NUMB_MOUSE (235-566): 5.47e-63: 220: 15.88		LNX1_MOUSE (1-728): 8.14e-134: 414: 87.98
+	Hs
		269170 DAB1_HUMAN (232-533): 8.11e-53: 191: 15.53		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Mm
		140100 NUMBL_MOUSE (185-540): 1.06e-67: 232: 16.85		LNX2_MOUSE (1-728): 4.94e-115: 364: 45.62
+	Mm
		1265184 NUMB_MOUSE (235-566): 5.47e-63: 220: 15.88		LNX2_MOUSE (1-728): 4.94e-115: 364: 45.62
+	Hs
		833625 NUMB_HUMAN (235-541): 6.02e-61: 214: 15.22		LNX2_HUMAN (3-728): 5.7e-116: 366: 45.21
+	Mm
		887083 ANS1A_MOUSE (1-493): 1.04e-141: 440: 87.42		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Mm
		1143409 Q8BZM2_MOUSE (17-497): 2.19e-146: 431: 52.55		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Mm
		1143393 ANS1B_MOUSE (1-497): 3.93e-137: 430: 52.65		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Hs
		833631 NUMB_HUMAN (235-541): 6.02e-61: 214: 15.22		PARD3_HUMAN (247-554): 1.39e-32: 137: 20.96
+	Rn
		957050 Q3MUI2_RAT (185-540): 8.59e-67: 229: 17.18		GRIP1_RAT (507-720): 1.63e-12: 73.2: 28.84
+	Mm
		1143503 CAPON_MOUSE (255-515): 5.07e-48: 176: 17.95		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Hs
		1132908 SH2D5_HUMAN (270-570): 1.8e-56: 197: 17.16		NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56
+	Hs
		253559 CAPON_HUMAN (255-505): 9.71e-48: 175: 17.91		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52