HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: LASP1 (Q61792)
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene: LASP1

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28469556
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ank_2~LIM, Ank_2~SH3_9, SH3_2~SH3_9
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1730 Mm			1 263
+	Rn
		1337443 SHAN3_RAT (1-1730): 0: 618: 98.39		DBNL_RAT (61-263): 2.84e-28: 113: 25.12
+	Hs
		1316309 SHAN3_HUMAN (1-1730): 0: 601: 95.21		DBNL_HUMAN (75-263): 6.35e-34: 128: 24.23
+	Mm
		1115943 SHAN3_MOUSE (1-1730): 0: 626: 100.00		SH3G2_MOUSE (53-263): 8.47e-24: 100: 16.96
+	Mm
		1115930 SHAN3_MOUSE (1-1730): 0: 626: 100.00		PACN1_MOUSE (13-263): 8.18e-23: 98.4: 18.05
+	Hs
		581050 SHAN3_HUMAN (1-1730): 0: 601: 95.21		PLCG1_HUMAN (14-263): 6.66e-24: 102: 16.40
+	Hs
		1307432 SHAN3_HUMAN (1-1730): 0: 601: 95.21		SH3G2_HUMAN (59-263): 1.69e-23: 99.6: 18.35
+	Hs
		1052307 SHAN3_HUMAN (1-1730): 0: 601: 95.21		SRC8_HUMAN (42-262): 8.52e-23: 99.2: 21.46
+	Hs
		1307450 SHAN3_HUMAN (1-1730): 0: 601: 95.21		SH3G3_HUMAN (57-263): 2.02e-23: 99.2: 20.85
+	Hs
		1078902 SHAN3_HUMAN (1-1730): 0: 601: 95.21		ITSN1_HUMAN (38-263): 2.37e-13: 71.8: 14.59
+	Hs
		235585 SHAN3_HUMAN (1-1730): 0: 601: 95.21		VINEX_HUMAN (197-262): 3.25e-10: 61.9: 25.71
+	Hs
		298999 SHAN3_HUMAN (1-1730): 0: 601: 95.21		SRBS2_HUMAN (150-261): 1.41e-09: 60.3: 27.68
+	Hs
		581080 SHAN2_HUMAN (8-1727): 2.64e-135: 466: 40.52		PLCG1_HUMAN (14-263): 6.66e-24: 102: 16.40
+	Hs
		1052351 SHAN2_HUMAN (8-1727): 2.64e-135: 466: 40.52		SRC8_HUMAN (42-262): 8.52e-23: 99.2: 21.46
+	Hs
		862039 DAPK1_HUMAN (17-450): 1.03e-87: 318: 15.97		SRC8_HUMAN (42-262): 8.52e-23: 99.2: 21.46
+	Hs
		167009 ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60		SH3G3_HUMAN (57-263): 2.02e-23: 99.2: 20.85
+	Hs
		1078859 MIB1_HUMAN (187-625): 7.14e-50: 195: 10.66		ITSN1_HUMAN (38-263): 2.37e-13: 71.8: 14.59