HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 27507650, 28671696, 29111324, 36417873, 36604605, 28469556
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~SH3_1, PDZ~PDZ_6, PDZ~SAM_1, Guanylate_kin~SH3_2, PDZ~SH3_2, SH3_1~SH3_2
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007626 - locomotory behavior
GO:0014069 - postsynaptic density
GO:0035176 - social behavior
and 17 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1730
Mm

1 724
+ Mm
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+ Mm
+ Mm
+ Rn
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+ Ce
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+ Hs

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Last updated: 15 Jul 2024