HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: CYFP1 (Q7TMB8)
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1)
Gene: Cyfip1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27507650, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043005 - neuron projection GO:0043197 - dendritic spine GO:0060076 - excitatory synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1730 Mm			1 1253
+	Mm
		1115910 SHAN3_MOUSE (1-1730): 0: 626: 100.00		CYFP2_MOUSE (1-1253): 0: 2084: 87.31
+	Mm
		1131077 CSKI1_MOUSE (55-1397): 7.52e-114: 397: 15.53		CYFP2_MOUSE (1-1253): 0: 2084: 87.31
+	Hs
		1206023 MIB1_HUMAN (187-625): 7.14e-50: 195: 10.66		CYFP2_HUMAN (1-1253): 0: 2075: 85.68
+	Mm
		88372 SHAN1_MOUSE (367-1725): 5.86e-28: 126: 14.36		CYFP1_MOUSE (1-1253): 0: 2088: 100.00
+	Mm
		88369 SHAN1_MOUSE (367-1725): 5.86e-28: 126: 14.36		CYFP2_MOUSE (1-1253): 0: 2084: 87.31
+	Mm
		1186394 ANK2_MOUSE (134-335): 6.85e-09: 63.5: 31.19		CYFP1_MOUSE (1-1253): 0: 2088: 100.00