HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: MAP6 (Q7TSJ2)
Microtubule-associated protein 6 (MAP-6) (Stable tubule-only polypeptide) (STOP)
Gene: MAP6

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043005 - neuron projection
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1730 Mm			1 906
+	Mm
		93248 SHAN3_MOUSE (1-1730): 0: 626: 100.00		E9PWQ7_MOUSE (436-899): 2.19e-37: 155: 13.52
+	Mm
		1116160 SHAN3_MOUSE (1-1730): 0: 626: 100.00		PCLO_MOUSE (145-906): 2.67e-25: 116: 8.85
+	Mm
		936894 SHAN3_MOUSE (1-1730): 0: 626: 100.00		NACAM_MOUSE (23-904): 1.9e-19: 96.8: 9.49
+	Mm
		1116022 SHAN3_MOUSE (1-1730): 0: 626: 100.00		ANK2_MOUSE (248-709): 4.26e-10: 66.2: 16.60
+	Mm
		88456 SHAN3_MOUSE (1-1730): 0: 626: 100.00		D3Z656_MOUSE (182-724): 8.78e-10: 64.8: 9.96
+	Hs
		1056981 TNKS2_HUMAN (1-544): 1.02e-87: 315: 15.16		MDC1_HUMAN (25-856): 2.89e-33: 141: 10.85
+	Hs
		310053 TNKS1_HUMAN (12-400): 2.92e-79: 291: 16.63		MDC1_HUMAN (25-856): 2.89e-33: 141: 10.85
+	Hs
		862028 DAPK1_HUMAN (17-450): 1.03e-87: 318: 15.97		ANK2_HUMAN (302-896): 6.99e-11: 68.9: 17.06
+	Mm
		103609 ANK3_MOUSE (41-592): 7.79e-85: 311: 15.58		MICA3_MOUSE (404-846): 4.53e-13: 75.8: 14.10
+	Hs
		1115387 AKD1A_HUMAN (21-460): 3.05e-91: 309: 15.61		TITIN_HUMAN (70-750): 2.45e-11: 70.2: 9.52
+	Mm
		103608 ANK3_MOUSE (41-592): 7.79e-85: 311: 15.58		ANK2_MOUSE (248-709): 4.26e-10: 66.2: 16.60
+	Dm
		65570 A8JNM5_DROME (19-638): 1.13e-74: 279: 14.72		FUTSC_DROME (38-906): 6.25e-09: 62.3: 10.62
+	Dm
		1361443 Q9VAU5_DROME (149-873): 9.98e-65: 246: 10.69		Q9VLS7_DROME (46-905): 4.94e-12: 72.5: 9.80
+	Hs
		965154 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		ANK2_HUMAN (302-896): 6.99e-11: 68.9: 17.06
+	Hs
		883487 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		ANK2_HUMAN (302-896): 6.99e-11: 68.9: 17.06
+	Hs
		965138 ANK2_HUMAN (212-349): 7.67e-29: 129: 24.64		MAP6_HUMAN (1-805): 3.82e-44: 174: 38.37
+	Hs
		556716 ANK1_HUMAN (175-669): 2.17e-43: 176: 15.35		TITIN_HUMAN (70-750): 2.45e-11: 70.2: 9.52
+	Hs
		166985 ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60		TITIN_HUMAN (70-750): 2.45e-11: 70.2: 9.52
+	Hs
		166913 ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60		ANK2_HUMAN (302-896): 6.99e-11: 68.9: 17.06
+	Dm
		1182373 Q7KU92_DROME (177-544): 6.44e-41: 169: 14.95		Q9VLS7_DROME (46-905): 4.94e-12: 72.5: 9.80