HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: BAIP2 (Q8BKX1)
BAR/IMD domain-containing adapter protein 2 (Brain-specific angiogenesis inhibitor 1-associated protein 2) (BAI-associated protein 2) (BAI1-associated protein 2) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53) (Insulin receptor tyrosine kinase 53 kDa substrate)
Gene: Baiap2

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 27507650, 28671696, 29111324, 28469556
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_2~SH3_2
Common GO terms GO:0043005 - neuron projection
GO:0043197 - dendritic spine
GO:0048167 - regulation of synaptic plasticity
GO:0050804 - modulation of chemical synaptic transmission
GO:0060076 - excitatory synapse
and 5 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1730
Mm

1 535
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024