HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: TENR (Q8BYI9)
Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin)
Gene: Tnr

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 28671696, 28469556
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~fn3
Common GO terms GO:0008306 - associative learning
GO:0035641 - locomotory exploration behavior
GO:0050804 - modulation of chemical synaptic transmission
GO:0050885 - neuromuscular process controlling balance
GO:0051968 - positive regulation of synaptic transmission, glutamatergic
and 2 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1730
Mm

1 1358
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024