HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: ANK2 (Q8C8R3)
Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin)
Gene: ANK2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 27507650, 28671696, 36417873
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ank_2, Ank_2~Ank_2, Ank_2~Ank_4
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0045211 - postsynaptic membrane
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1730
Mm

1 3898
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Last updated: 15 Jul 2024