HitPredict

Interactor 1: K7EMM4 (K7EMM4)
Transcription factor E2-alpha (Transcription factor 3)
Gene: TCF3

Interactor 2: ID1 (P41134)
DNA-binding protein inhibitor ID-1 (Class B basic helix-loop-helix protein 24) (bHLHb24) (Inhibitor of DNA binding 1) (Inhibitor of differentiation 1)
Gene: ID1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005654 - nucleoplasm GO:0046983 - protein dimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 220 Hs			1 155
+	Hs
		551478 TFE2_HUMAN (2-220): 6.36e-123: 364: 89.19		ID1_HUMAN (1-155): 1.17e-77: 229: 100.00
+	Mm
		550218 TFE2_MOUSE (2-220): 3.77e-112: 336: 77.58		Q6GTZ3_MOUSE (15-155): 1.41e-70: 211: 90.78
+	Mm
		550178 TFE2_MOUSE (2-220): 3.77e-112: 336: 77.58		ID1_MOUSE (15-142): 2.25e-63: 193: 89.84
+	Hs
		551502 TFE2_HUMAN (2-220): 6.36e-123: 364: 89.19		ID2_HUMAN (19-154): 3.39e-45: 146: 42.07
+	Hs
		551503 TFE2_HUMAN (2-220): 6.36e-123: 364: 89.19		ID3_HUMAN (19-128): 1.94e-45: 146: 47.27
+	Hs
		551084 ITF2_HUMAN (5-220): 4.56e-87: 272: 52.86		ID1_HUMAN (1-155): 1.17e-77: 229: 100.00
+	Mm
		1142448 HTF4_MOUSE (7-220): 1.71e-87: 273: 53.74		Q6GTZ3_MOUSE (15-155): 1.41e-70: 211: 90.78
+	Mm
		550184 TFE2_MOUSE (2-220): 3.77e-112: 336: 77.58		ID2_MOUSE (19-154): 3.1e-46: 148: 41.38
+	Mm
		550183 TFE2_MOUSE (2-220): 3.77e-112: 336: 77.58		ID3_MOUSE (19-128): 8.16e-46: 147: 46.36
+	Rn
		600264 TFE2_RAT (2-220): 2.21e-111: 334: 77.13		ID3_RAT (19-128): 2.16e-45: 146: 46.36
+	Hs
		551480 TFE2_HUMAN (2-220): 6.36e-123: 364: 89.19		ID4_HUMAN (19-155): 1.46e-32: 114: 34.94
+	Mm
		589142 Q91XK1_MOUSE (5-220): 2.44e-91: 278: 53.25		ID1_MOUSE (15-142): 2.25e-63: 193: 89.84
+	Mm
		781009 Q91XK1_MOUSE (5-220): 2.44e-91: 278: 53.25		ID2_MOUSE (19-154): 3.1e-46: 148: 41.38
+	Mm
		780947 Q91XK1_MOUSE (5-220): 2.44e-91: 278: 53.25		ID3_MOUSE (19-128): 8.16e-46: 147: 46.36
+	Mm
		781007 HTF4_MOUSE (7-220): 1.71e-87: 273: 53.74		ID2_MOUSE (19-154): 3.1e-46: 148: 41.38
+	Mm
		780945 HTF4_MOUSE (7-220): 1.71e-87: 273: 53.74		ID3_MOUSE (19-128): 8.16e-46: 147: 46.36
+	Mm
		780944 ITF2_MOUSE (5-220): 2.89e-87: 272: 53.25		ID3_MOUSE (19-128): 8.16e-46: 147: 46.36
+	Hs
		551118 ITF2_HUMAN (5-220): 4.56e-87: 272: 52.86		ID2_HUMAN (19-154): 3.39e-45: 146: 42.07
+	Hs
		551119 ITF2_HUMAN (5-220): 4.56e-87: 272: 52.86		ID3_HUMAN (19-128): 1.94e-45: 146: 47.27
+	Hs
		551089 ITF2_HUMAN (5-220): 4.56e-87: 272: 52.86		ID4_HUMAN (19-155): 1.46e-32: 114: 34.94