HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: LAR1B (Q659C4)
La-related protein 1B (La ribonucleoprotein domain family member 1B) (La ribonucleoprotein domain family member 2) (La-related protein 2)
Gene: LARP1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	29845934, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 914
+	Hs
		1116331 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		516553 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		LAR1B_HUMAN (1-914): 0: 921: 100.00
+	Hs
		403258 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		1031367 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		516561 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		1116423 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		LAR4B_HUMAN (95-701): 2.54e-81: 280: 10.36
+	Hs
		403248 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		LA_HUMAN (215-628): 1.98e-59: 210: 17.78
+	Hs
		516568 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		LARP4_HUMAN (114-703): 1.5e-97: 323: 13.29
+	Hs
		1031407 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		LAR4B_HUMAN (95-701): 2.54e-81: 280: 10.36
+	Hs
		1174826 LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32		LAR4B_HUMAN (95-701): 2.54e-81: 280: 10.36
+	Hs
		516616 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		LAR4B_HUMAN (95-701): 2.54e-81: 280: 10.36
+	At
		790116 PABP2_ARATH (25-486): 1.23e-63: 222: 11.70		LRP6C_ARATH (130-445): 7.11e-55: 199: 14.83
+	At
		285476 PABP2_ARATH (25-486): 1.23e-63: 222: 11.70		LRP6B_ARATH (111-447): 3.39e-49: 185: 12.36
+	Dm
		597071 PABP_DROME (28-516): 8.3e-58: 206: 12.35		LARP_DROME (37-408): 4.22e-45: 179: 21.75
+	Hs
		403212 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		LA_HUMAN (215-628): 1.98e-59: 210: 17.78
+	Hs
		1116542 PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1031352 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		516541 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Sc
		704881 LHP1_YEAST (7-270): 1.34e-45: 163: 22.74		LHP1_YEAST (212-447): 8.47e-35: 136: 15.20