HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: DHX57 (Q6P158)
Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57)
Gene: DHX57

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26725010, 29845934, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 582 Hs			1 1386
+	Hs
		1158090 LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02		DHX57_HUMAN (29-1386): 0: 1536: 100.00
+	Hs
		1158103 PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15		DHX57_HUMAN (29-1386): 0: 1536: 100.00
+	Hs
		1116361 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		DHX29_HUMAN (231-1386): 0: 940: 32.11
+	Hs
		994194 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		DHX9_HUMAN (269-1383): 0: 894: 29.56
+	Hs
		1116540 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		DHX36_HUMAN (395-1386): 0: 863: 37.98
+	Hs
		195457 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		DHX15_HUMAN (492-1331): 0: 785: 24.70
+	Hs
		1116346 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		DHX30_HUMAN (473-1361): 0: 709: 30.91
+	Hs
		403200 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		DHX9_HUMAN (269-1383): 0: 894: 29.56
+	Hs
		1116379 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		DHX37_HUMAN (524-1329): 0: 666: 24.53
+	Bt
		898864 PABP1_BOVIN (1-405): 1.94e-40: 157: 10.29		DHX9_BOVIN (270-1383): 0: 886: 29.76
+	Hs
		403338 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		DHX36_HUMAN (395-1386): 0: 863: 37.98
+	Hs
		1268165 LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02		DHX36_HUMAN (395-1386): 0: 863: 37.98
+	Sc
		376861 PABP_YEAST (9-243): 8.44e-33: 134: 13.47		PRP43_YEAST (452-1338): 0: 757: 25.11
+	Hs
		403266 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		DHX30_HUMAN (473-1361): 0: 709: 30.91
+	Sc
		704911 LHP1_YEAST (7-270): 1.34e-45: 163: 22.74		DHR1_YEAST (417-1320): 0: 681: 22.58
+	Sc
		376941 PABP_YEAST (9-243): 8.44e-33: 134: 13.47		YL419_YEAST (473-1386): 0: 685: 26.16
+	Sc
		376924 PABP_YEAST (9-243): 8.44e-33: 134: 13.47		DHR1_YEAST (417-1320): 0: 681: 22.58
+	Hs
		1222148 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		DHX37_HUMAN (524-1329): 0: 666: 24.53
+	Hs
		1116549 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		YTDC2_HUMAN (513-741): 5.46e-59: 226: 51.87
+	Hs
		1316880 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		YTDC2_HUMAN (513-741): 5.46e-59: 226: 51.87