HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: PABP2 (Q86U42)
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)
Gene: PABPN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 582 Hs			1 306
+	Hs
		853916 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	Hs
		1047867 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15
+	Hs
		958197 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		RBM3_HUMAN (167-304): 1.15e-32: 119: 22.45
+	Hs
		1116304 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PAP1L_HUMAN (66-260): 2.53e-23: 101: 12.25
+	Hs
		516541 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		1031352 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		1116542 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PABP3_HUMAN (59-260): 1.51e-19: 90.7: 11.82
+	Hs
		1116403 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		ZCRB1_HUMAN (170-286): 1.58e-16: 78.7: 27.97
+	At
		285476 LRP6B_ARATH (2-265): 6.42e-54: 194: 21.20		PABP2_ARATH (144-260): 4.68e-21: 95.4: 18.64
+	At
		285478 LRP6B_ARATH (2-265): 6.42e-54: 194: 21.20		PABP8_ARATH (171-260): 1.74e-19: 90.7: 21.98
+	Hs
		853881 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	At
		790116 LRP6C_ARATH (12-249): 1.53e-49: 179: 23.14		PABP2_ARATH (144-260): 4.68e-21: 95.4: 18.64
+	Hs
		516689 PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		403212 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		516495 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		516339 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		516568 LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Sc
		376709 LHP1_YEAST (7-270): 1.34e-45: 163: 22.74		PABP_YEAST (143-260): 3.27e-19: 89.6: 20.17
+	Hs
		403292 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		ZCRB1_HUMAN (170-286): 1.58e-16: 78.7: 27.97
+	Sc
		693977 LHP1_YEAST (7-270): 1.34e-45: 163: 22.74		PUB1_YEAST (165-255): 5.29e-09: 58.8: 18.48