HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: CDK20 (Q8IZL9)
Cyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H) (Cyclin-kinase-activating kinase p42)
Gene: CDK20

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 346
+	Hs
		625477 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10
+	Hs
		960098 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK3_HUMAN (1-308): 3.83e-138: 395: 44.66
+	Hs
		414946 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK1_HUMAN (1-292): 1.16e-131: 379: 42.18
+	Hs
		960291 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK5_HUMAN (1-294): 2.23e-128: 370: 45.09
+	At
		1103363 LRP1A_ARATH (10-367): 4.77e-56: 204: 16.85		CKB12_ARATH (1-290): 2.93e-129: 373: 40.58
+	Hs
		403088 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10
+	Hs
		516362 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10
+	Hs
		841320 PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11		CDK7_HUMAN (3-304): 2.01e-127: 370: 42.62
+	Sc
		339316 PABP_YEAST (9-243): 8.44e-33: 134: 13.47		CDK1_YEAST (3-291): 1.14e-124: 361: 42.71
+	Dm
		582590 SXL_DROME (59-259): 1.13e-24: 107: 20.29		CDK2_DROME (1-290): 2.59e-128: 371: 41.72
+	Hs
		841335 RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84		CDK7_HUMAN (3-304): 2.01e-127: 370: 42.62
+	At
		1321248 PABP8_ARATH (2-127): 5.76e-15: 80: 11.91		CDKD2_ARATH (1-346): 2.58e-129: 375: 41.79
+	Hs
		414931 ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50		CDK1_HUMAN (1-292): 1.16e-131: 379: 42.18
+	Hs
		841210 ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50		CDK7_HUMAN (3-304): 2.01e-127: 370: 42.62