HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: BARD1 (Q99728)
BRCA1-associated RING domain protein 1 (BARD-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BARD1)
Gene: BARD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	32726637, 22990118
Identification Methods	affinity chromatography technology, protein complementation assay, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 777
+	Hs
		403322 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		BARD1_HUMAN (1-777): 0: 663: 100.00
+	Hs
		1162660 LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23		BARD1_HUMAN (1-777): 0: 663: 100.00
+	Hs
		1116503 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		SLF1_HUMAN (423-552): 2.06e-17: 89.4: 43.80
+	Hs
		965152 PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11		ANK2_HUMAN (104-622): 2.47e-71: 257: 14.31
+	Hs
		257638 LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32		ANR17_HUMAN (177-599): 3.04e-64: 236: 15.72
+	Hs
		1219801 LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02		ANKH1_HUMAN (114-664): 2.01e-66: 242: 14.16
+	Hs
		257675 LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02		ANR17_HUMAN (177-599): 3.04e-64: 236: 15.72
+	Hs
		1164783 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		ANR11_HUMAN (280-544): 1.17e-42: 170: 25.74